Run Time: 4 minutes
Author: Dr. Jared Scott
- A recent study in the NEJM looked at the efficacy of lidocaine and amiodarone for use in out-of-hospital cardiac arrest.
- About 1/3 of the 3000 participants in the trial were randomized to a placebo, 1/3 to amiodarone, and 1/3 to lidocaine. The primary outcomes used were survival to hospital discharge and good neurological function at discharge to indicate a favorable outcome.
- With amiodarone 24% of the patients had a favorable outcome, with lidocaine 24% of the patients had a favorable outcome, and with a placebo 21% of the patients had a favorable outcome. These findings bear no statistical significance to indicate benefits of using these drugs during out-of-hospital cardiac arrest.
- Jared’s take away – quick access to electricity and good, deep, uninterrupted CPR should not be sacrificed to push medications for patients in cardiac arrest.