Podcast #79: Fifth Disease

Run Time: 7 minutes

Author: Dr. Samuel Killian

Educational Pearls:

  • Presentation: A fever and nasal congestion that began in an infant one week ago but has resolved. A rash that was predominantly over the cheeks but has spread to the rest of the body. No pain with the rash, just blistering.
  • Diagnosis: Fifth disease or erythema infectiosum, which it is caused by parovirus B19. This disease’s first phase starts with “slap-cheek” rash that lasts 1-4 days, which moves to the extremities and then to the trunk. The second phase consists of the formation of a reticular rash. In the third phase, the rash comes and goes depending on whether and activity.
  • Around 75% of people have parovirus B19 in their body, although it is almost always benign.
  • The virus can cross both the brain-barrier and the placental-barrier, causing complications in people with thalassemia and women who are pregnant.
  • 1 to 9 of all miscarriages are believed to be caused by this parovirus.

Link to Podcast: http://medicalminute.madewithopinion.com/fifth-disease-1/

References: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2793222/

http://www.ncbi.nlm.nih.gov/pubmed/2160748

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