Contributor: Aaron Lessen, MD
- Supplemental oxygen is not a completely benign intervention.
- A recent meta-analysis found that O2 saturations above 96% while on supplemental O2 were associated with worse outcomes.
- Only start a patient on supplemental oxygen if absolutely necessary and aim for a goal of no higher than 96%.
Derek K Chu, Lisa H-Y Kim, Paul J Young, Nima Zamiri, Saleh A Almenawer, Roman Jaeschke, Wojciech Szczeklik, Holger J Schünemann, John D Neary, Waleed Alhazzani. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. The Lancet. Volume 391, Issue 10131. 2018. Pages 1693-1705,
Summarized by Will Dewispelaere, MD | Edited by Erik Verzemnieks, MD