Podcast 570: Oh no no no to O2 - The Emergency Medical Minute

Podcast 570: Oh no no no to O2

Contributor: Aaron Lessen, MD

Educational Pearls:

  • Supplemental oxygen is not a completely benign intervention. 
  • A recent meta-analysis found that O2 saturations above 96% while on supplemental O2 were associated with worse outcomes.
  • Only start a patient on supplemental oxygen if absolutely necessary and aim for a goal of no higher than 96%.


Derek K Chu, Lisa H-Y Kim, Paul J Young, Nima Zamiri, Saleh A Almenawer, Roman Jaeschke, Wojciech Szczeklik, Holger J Schünemann, John D Neary, Waleed Alhazzani. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis. The Lancet. Volume 391, Issue 10131. 2018. Pages 1693-1705,


Summarized by Will Dewispelaere, MD | Edited by Erik Verzemnieks, MD

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