Author: Don Stader, MD
- Cyclic vomiting syndrome (CVS) is different than cannabis hyperemesis syndrome (CHS). It is important to differentiate the two.
- CHS is thought to be caused by activation of THC receptors in the gut
- CVS is associated with migraines and therefore responds to similar medications
- Olanzapine (Zyprexa) is an alternative to haloperidol (Haldol)
- Amitriptyline, as well as anti-epileptics can be used to prevent CVS
- Opioids worsen CVS
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Boles RG, Lovett-Barr MR, Preston A, Li BU, Adams K. Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. BMC Neurol. 2010;10:10. Epub 2010 Jan 28.
Hikita T, Kodama H, Kaneko S, Amakata K, Ogita K, Mochizuki D, Kaga F, Nakamoto N, Fujii Y, Kikuchi A. Sumatriptan as a treatment for cyclic vomiting syndrome: a clinical trial. Cephalalgia. 2011;31(4):504. Epub 2010 Dec 8.
Summarized by Will Dewispelaere, MS3 | Edited by Erik Verzemnieks, MD