Podcast #402: Rapid sequence intubation medications - The Emergency Medical Minute

Educational Pearls:

  • RSI includes induction agent (sedative) and a paralytic
  • Succinylcholine is a depolarizing paralytic of rapid onset and short duration with contraindications in hyperkalemic states and muscular dystrophy
  • Rocuronium and vecuronium are longer acting, non-depolarizing paralytic, more commonly
  • Common induction agents are etomidate and ketamine
  • Ketamine can be particularly beneficial for bronchodilator effects in those with reactive airway disease



Stollings JL, Diedrich DA, Oyen LJ, Brown DR. Rapid-sequence intubation: a review of the process and considerations when choosing medications. Ann Pharmacother. 2014 Jan;48(1):62-76. doi: 10.1177/1060028013510488. Epub 2013 Nov 4. Review. PubMed PMID: 24259635.

Summary by Travis Barlock, MS4  | Edited by Erik Verzemnieks, MD

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