Author: Rachel Beham, PharmD
- Some synthetic cannabinoids have been contaminated with Brodifacoum. Brodifacoum is a Vitamin K antagonist and can present with a severe coagulopathy.
- Brodifacoum is commonly known as “superwarfarin” and has a very long half life of 120+ days.
- Check PT/INR in patients with a bleeding diathesis in setting of synthetic cannabinoid use.
- Treatment is activated charcoal and large doses of Vitamin K (10mg Q6H for months).
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