Author: Nick Hatch, M.D.
- Tramadol acts at multiple receptors and is a partial agonist at the mu opioid receptor, but also blocks reuptake of serotonin and norepinephrine throughout the body among others.
- One major side effect to be aware of is that it lowers the seizure threshold.
- Useful in setting of pain control in patients with contraindications to NSAIDs who are poor opioid candidates.
- Use with caution as it potential for abuse.
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