Author: John Winkler, M.D.
- Normally, the parathyroid is the master regulator of serum Ca levels. It secretes PTH, which stimulates calcium uptake from the bone and gut.
- Causes of hypercalcemia include: parathyroid tumor, lytic bone lesions (multiple myeloma), breast cancer, renal injury, and some lung cancers.
- Hypercalcemia can lead to poor bone quality and pathological fractures. It can also cause heart arrhythmias.
- It is important to order an ionized calcium to quantify the level of hypercalcemia, since calcium binds to albumin.
- Treatment for hypercalcemia includes fluids and loop diuretics.