Podcast #2: Buprenorphine - The Emergency Medical Minute

Podcast #2: Buprenorphine


Run Time: 4 minutes

Author: Dr. Jared Scott

Educational Pearls:

  • Semi-synthetic methadone used for chronic pain and nausea treatment.
  • Partial agonist to opioid receptors, which decreases respiratory depression – theoretically decreases likelihood of respiratory arrest in a patient who overdoses.
  • Patients on Buprenorphine chronically need Sufentanil for surgery – 10 times more potent than Fentanyl and 100 times more potent than Morphine.
  • Buprenorphine is the main ingredient in Suboxone – 4:1 ratio of Buprenorphine and Narcan – used by patients trying to get off of narcotics.

References:  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a5edcf9-828c-4f97-b671-268ab13a8ecd

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