Podcast #121:  The Poor Man’s Methadone

51hafn56t9l-_sy300_Run Time: 3 minutes

Author: Nicholas Hatch M.D.

Educational Pearls:

  • Imodium is sometimes referred to as “the poor man’s methadone” as it does work on opioid receptors. It works on opioid receptors in the abdomen, which is why it is used to reduce the frequency of diarrhea. But in very high doses can affect opioid receptors in the brain and other areas.
  • In overdose it can also cause arrhythmias on EKGs including QT elongation and QRS elongation.
  • The abuse of Imodium in high doses has been linked to sudden death occurrences and is a worrisomely growing trend given the opioid epidemic.

Link to Podcast:  http://medicalminute.madewithopinion.com/the-poor-man-s-methadone/

References:  http://www.ncbi.nlm.nih.gov/pubmed/26355852

http://www.ncbi.nlm.nih.gov/pubmed/25645123

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