Podcast #119: Status Epilepticus

epilepsy-graphicRun Time: 2 minutes

Author: Samuel Killian M.D.

Educational Pearls:

  • First line of treatment for status epilepticus is benzodiazepines. Typically two doses of 4mg of ativan is given for adults and 0.1 mg per kg is given for children.
  • Second, think P! Try one of either phenytoin, fosphenytoin, phenobarbital, and keppra, given at about 15-20 mg per kg depending on the specific drug used. If not working, try your second favorite.
  • As the third line of treatment, consider a versed drip, propofol, barbiturate coma, and start thinking about giving pyridoxine for possible ingestion. These patients are typically intubated and will usually require a continuous EEG to monitor for continued seizure activity.

Link to Podcast: http://medicalminute.madewithopinion.com/status-epilepticus/

References:  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824929/

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