Podcast #77: Purpura

c5f8db53-cbd5-4959-bf81-da4c457765c1Run Time: 14 minutes

Author: Dr. Donald Stader

Educational Pearls:

  • When a patient comes in with purpura the way to think is outside in, because there is a long list of things that can cause purpura.
  • The most common cause of purpura is trauma.
  • The next level is a blood vessel problem; Ehler’s-Danlos Syndrome, Vitamin C deficiency.
  • Coagulation disorders is the 3rd level; hemophilia, coagulopathy (drugs are a big cause), low platelet counts (such as ITP)
  • The most serious problems are often acquired and purpura could be a potentially deadly manifestation – such as HUS (caused by E. coli O157:H7), bacterial meningitis (meningococcus), leukemia/lymphoma, HSP.
  • Often children are more seriously affected when they have purpura – importnant to check CBC, PT INR, and a BMP to evaluate for kidney function.

Link to Podcast:  http://medicalminute.madewithopinion.com/purpua/

References:  http://www.aafp.org/afp/2008/0415/p1117.html

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